Loss of heterozygosity analysis to diagnose adrenal cortical carcinoma
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چکیده
منابع مشابه
Loss of somatic heterozygosity in hepatocellular carcinoma.
Loss of tumor suppressor genes is involved in the mechanism of tumorigenesis of many solid tumors. We tested 9 hepatitis B virus (HBV)-positive and 10 HBV-negative hepatocellular carcinomas for loss of somatic heterozygosity using 14 polymorphic probes mapping to chromosomes 4, 11, 13, and 17. Losses were found on all chromosome arms tested. The highest frequency of loss was observed at the D13...
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One reference to the transplantation of an adrenal cortical tumor of the mouse has been found in the literature. Dalton, Edwards, and Andervont (1) reported on a spontaneous, transplantable, adrenal cortical tumor in a female strain C mouse 24 89 months of age. They presented evidence that this neoplasm originated from relatively undifferentiated cells of the adrenal cortex. The failure to find...
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1. Schoenberg BS, Mellinger JF, Schoenberg DG. Cerebrovascular disease in infants and children:A study of incidence, clinical features and survival. Neurology 1978; 28:763-8. 2. Mitra S, Ghosh D, Puri R, Parmar VR. Top-ofthe-basi lar-ar tery stroke. Indian Pediatr 2001;38:83-7. 3. Nagaraja D, Verma A, Taly AB, Kumar MV, Jayakumar PN. Cerebrovascular disease in children. Acta Neurol Scand 1994;9...
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This article reviews adrenal cortical carcinoma (ACC), especially associated synchronous and metachronous malignancies. The authors will discuss the genetic lesions associated with ACC, the clinical presentation, diagnosis, and treatment options. We hope to provide a thorough and updated review of this rare malignancy.
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ژورنال
عنوان ژورنال: Cancer
سال: 1999
ISSN: 0008-543X,1097-0142
DOI: 10.1002/(sici)1097-0142(19990825)87:4<173::aid-cncr1>3.0.co;2-c